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MAN1 mAb

This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

Alternative Name(s)

MAN1Inner nuclear membrane protein Man1; integral inner nuclear membrane protein; integral inner nuclear membrane protein MAN1; LEM domain-containing protein 3; MAN1;AI316861; LEMD3; MAN1

Uniport

Q9Y2U8

Source

Mouse

Clonality

Monoclonal

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